Clemson v. Boston College

You wouldn't think that a land-grant college in South Carolina and a Jesuit school in Boston would have that many games against each other. But this series actually goes back to the 1940 Cotton Bowl, when the Clemson program first obtained national recognition by upsetting B.C. by the score of 6 to 3. Since then the teams have played off and on throughout the years -- and they have played every year since B.C. joined the ACC in 2005. The series is tied: each team has a record of 9-9-2 against the other.

In recent years, these games have been quite competitive -- five of the six meetings since 2005 were decided by a touchdown or less. But B.C. is 1-4 this year, with their only win coming over UMass, a I-AA school. Meanwhile, Clemson is up to number 8 in the country thanks to its 5-0 record and its three consecutive wins over Auburn, Florida State, and Virginia Tech -- all of which were ranked in the AP poll when they played Clemson. Under these circumstances, Vegas has installed Clemson as a 21-point favorite to beat the Eagles and retain the UCFC. Given how impressive Clemson has been in recent weeks, it's hard to disagree with that analysis.